Micro flow cell: Body: 316L stainless steel Window: Proprietary material, optimized for bioprocesses Surface finish: Ra 15 with Electropolish to ASME BPE SF4 finish Adhesive: USP Class VI and ISO 10993 compatible
The Raman flow assembly brings in-line Raman spectroscopy to downstream bioprocessing. Comprised of a flow cell and associated flow bench connected to an Rxn-10 probe, this system meets the speed demands of downstream by optimizing Raman collection for low-turbidity, low volume samples. Ideally suited for development-scale flow rates, the Raman flow assembly provides real-time monitoring, rapid process optimization, and process control for chromatography and other downstream unit operations.
Downstream: aggregation, protein crystallization, formula stability, product CQA, protein concentration, buffer excipients
Midstream: analyte monitoring in permeate
Avantajlar
Brings Raman-based process insights and control to downstream bioprocessing unit operations
Achieves lower limits of detection through enhancement of the Raman signal
Provides continuous, real-time measurements with high sensitivity for development-scale flow rates
With the flow bench, provides flexibility to swap out flow cells any time without impacting your process or sterility
Raman spektroskopisi - gelişmiş optik analiz teknolojisi
Tesis güvenliğini artırın, ürün kalitesini sağlayın ve operasyonları optimize edin. Raman spektroskopisi, numunelerinizin bileşimini ve moleküler yapısını laboratuvardan prosese gerçek zamanlı olarak ölçer.
Micro flow bench: Operating: 0 to 40 °C / 32 to 104 °F Storage: -10 to 50 °C / 14 to 122 °F Micro flow cell: Operating: 0 to 40 °C / 32 to 104 °F Storage: -20 to 60 °C / -4 to 140 °F
Relative humidity
Micro flow cell: Storage: < 90 % Non-Condensing
Unit dimensions (width x height x depth)
Micro flow bench: 254 x 102 x 66 mm 10.0 x 4.0 x 2.6 inch Micro flow cell: 46 x 25 x 11 mm 1.8 x 1.0 x 0.4 inch
Sampling probe compatibility
Raman Rxn-10 in tandem
Sample interface
Micro flow bench: Micro flow cell
Pressure
Micro flow cell: Max pressure: 4.8 barg / 70 psig
Wetted materials
Micro flow cell: Body: 316L stainless steel Window: Proprietary material, optimized for bioprocesses Surface finish: Ra 15 with Electropolish to ASME BPE SF4 finish Adhesive: USP Class VI and ISO 10993 compatible
Sterilization method
Micro flow cell: CIP/SIP
Process connection
Micro flow cell: 5/16-24 flat bottom ferrules Up to 3/16 inch OD tubing
Fluid Path Thickness
Micro flow bench: 1.0 to 5.0 mm (flow cell driven) Micro flow cell: 2.5 mm
Raman flow assembly - Precise composition measurement of
high-speed, low-volume samples in downstream bioprocessing
PU (Yayın)
İngilizce versiyonu - 05/2023
New version available in English
An overview of the Raman flow assembly (flow bench and flow cell) used with the Rxn-10 probe in conjunction with a Raman Rxn2 analyzer and a Raman flow assembly calibration and verification kit for downstream bioprocessing (powered by Kaiser Raman technology).
Raman calibration and verification kits - Everything needed to
calibrate and verify your Raman analyzer system for lab-to-process
scalability
PU (Yayın)
İngilizce versiyonu - 12/2023
New version available in English
An overview of the Raman calibration and verification kits for the bio multi optic / single use optic and the Raman flow assembly (includes the flow bench and flow cell). These kits are to be used in conjunction with the Rxn-10 probe and Raman Rxn2 / Rxn4 analyzer for upstream and downstream bioprocessing (powered by Kaiser Raman technology).
Lab-to-process monitoring & control in Life Sciences -
Reliable measurement of bioprocess physical and
chemical properties
PU (Yayın)
İngilizce versiyonu - 04/2024
New version available in English
A combined product list of analysis offerings from both Optical Analysis and LIquid Analysis for bioprocessing applications in the life science industry (including Raman Rxn2 analyzer, Raman Rxn4 analyzer, Rxn-10 probe, bio multi optic and bio sleeve, Raman flow assembly, Rxn-45 probe, Rxn-46 probe, Raman optic system for single use, Memosens CPS61E, Memosens COS81E, OUSBT66, Memosens CPS61E, Memosens CPS77E, Memosens CLS82E, OUSAF44, Memosens CPS11E, Memosens CLS16E, TOC Analyzer CA79, Liquiline transmitter platform, and Memobase software).
Raman technology in bioprocessing - Scalable in situ bioprocess
monitoring enabling advanced process control
İnovasyon (IN)
İngilizce versiyonu - 06/2023
New version available in English
An overview brochure about our Raman spectroscopy analyzer and probe portfolio, powered by Kaiser Raman technology, for the bioprocessing / biopharmaceutical industry (including the Raman Rxn2 analyzer, Raman Rxn4 analyzer, Rxn-10 probe, Rxn-45 probe, Rxn-46 probe, and probe accessory optics (bIO-Optic, Raman single use optic system, bio multi optic with bio sleeve, and Raman flow assembly), powered by Kaiser Raman technology.
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